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KMID : 0882420150880010027
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Korean Journal of Medicine
2015 Volume.88 No. 1 p.27 ~ p.34
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Nonerosive Reflux Disease
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Kim Tae-Suk
Park Sung-Chul
Lee Sung-Joon
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Abstract
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Nonerosive reflux disease (NERD) is a distinct presentation of gastroesophageal reflux disease (GERD). NERD is commonly defined as the presence of classical GERD symptoms in the absence of esophageal mucosal erosions/breaks on upper endoscopy. Within the spectrum of GERD, the pathophysiological and clinical characteristics distinguishing NERD and erosive esophagitis remain a matter for debate. Recent research on NERD has focused on understanding the pathophysiology and natural history. Given the increased incidence of NERD in Korea, we reviewed the concept of NERD and its relationship to GERD and functional gastrointestinal disorders.
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KEYWORD
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Nonerosive reflux disease, Gastroesophageal reflux disease, Heartburn
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